Stop RNase Inhibitor

Stop RNase Inhibitor is a protein of non-human origin that binds non-covalently and inhibits the same types of ribonuclease as HPRI, including RNases A, B, and C. Stop RNase Inhibitor can be used in cDNA synthesis, in in vitro transcription using the SP6, T7, and HeLa cell extract systems, and in in vitro translations using rabbit reticulocyte lysates and wheat germ extracts. Additionally, Stop RNase Inhibitor prevents RNA degradation in cell extracts prepared under non-denaturing conditions, and may be utilized in first strand synthesis prior to PCR2 as well as in the RT-PCR of RNA isolated from single cells.

Product features;

• Inhibits greater than 90% of RNase activity, whereas Human
• Placental RNase Inhibitors (HPRI) inhibit only 50%
• Stable under a broad range of pH, DTT concentrations, and temperatures
• Inhibits RNases A, B, and C, similar to HPRI; does not interfere with RNases T1, T2, H, U1, U2, or CL3
• Sterile, DNase- and RNase-free